CD19 protein is a 95 kDa transmembrane glycoprotein that plays a central role in B cell activation and humoral immune responses . CD19 is expressed throughout B cell development from pre-B cells through mature B cells, and it is commonly used as a B cell lineage marker . It is required for the responsiveness of mature B cell to antigen stimulation, germinal center development, and antibody affinity matuRation . The CD19 protein associates with the B cell antigen receptor (BCR), CD81, CD38, CD21, CD22, and IFITM1/CD225/Leu13. These associations enable CD19 to amplify B cell signaling and reduce the threshold for antigen stimulation through the BCR.

Dettagli prodotto

• Codice: AN008610_50mg
• Marca: Elabscience
• Specie target: Human
• Host: Mouse
• Concentrazione: ≥ 1 mg/mL
• Link: Apri link
• Stoccaggio: Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
• Isotipo: Mouse IgG1, κ
• Clonalità: Monoclonal
• Clone: HIB19
• Applicazione: FCM
• Simbolo target: CVID;B-lymphocyteantigenCD;B-lymphocyte antigen CD;T-cellsurfaceantigenLeu;Differentiation antigen CD;T-cell surface antigen Leu;B-lymphocytesurfaceantigenB;B-lymphocyte surface antigen B;B4;CVID3;CD19;B-lymphocyteantigenCD19;B-lymphocytesurfaceantigenB4;T-cellsurfaceantigenLeu-12;B-lymphocyte antigen CD19;B-lymphocyte surface antigen B4;Differentiation antigen CD19;T-cell surface antigen Leu-12;B4;CVID3;CD19;CD19 molecule
• Area di ricerca: Immunology;Stem Cells