NK-1.1 surface antigen, also known as CD161b/CD161c and Ly-55, is encoded by the NKR-P1B/NKR-P1C gene. It is expressed on NK cells and NK-T cells in some mouse strains, including C57BL/6, FVB/N, and NZB, but not AKR, BALB/c, CBA/J, C3H, DBA/1, DBA/2, NOD, SJL, and 129. Expression of NKR-P1C antigen has been correlated with lysis of tumor cells in vitro and rejection of bone marrow allografts in vivo. NK-1.1 has also been shown to play a role in NK cell activation, IFN-γ production, and cytotoxic granule release. NK-1.1 and DX5 are commonly used as mouse NK cell markers.

Codice: E-AB-F09870_25μg | Marca: Elabscience | Confezionamento: 25μg

Specie: MouseIsotipo: Mouse IgG2a, κClone: PK136
Note

Recombinant Mouse NK1.1 protein

Dettagli prodotto
  • Codice: E-AB-F09870_25μg
  • Marca: Elabscience
  • Specie target: Mouse
  • Host: Mouse
  • Concentrazione: ≥ 1 mg/mL
  • Link: Apri link
  • Stoccaggio: Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
  • Isotipo: Mouse IgG2a, κ
  • Clonalità: Monoclonal
  • Clone: PK136
  • Applicazione: FCM
  • Simbolo target: CD161 antigen-like family member C;CD161/NK1.1;CD161c;Killer cell lectin-like receptor subfamily B member 1C;Klrb1c;Ly-55c;NKR-P1 40;NKR-P1.9;NKR-P1C
  • Area di ricerca: Immunology;Innate Immunity