CD3, also known as T3, is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3 is composed of CD3ε, δ, γ and ζ chains. It forms a TCR complex by associating with TCR α/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex.

Dettagli prodotto

• Codice: E-AB-F10130_50mg
• Marca: Elabscience
• Specie target: Mouse
• Host: Rat
• Concentrazione: ≥ 1 mg/mL
• Link: Apri link
• Stoccaggio: Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
• Isotipo: Rat IgG2b, κ
• Clonalità: Monoclonal
• Clone: 17A2
• Applicazione: FCM
• Simbolo target: CD3;CD3E/D/G/Z;CD3e/d/g/z;T-cell surface glycoprotein CD 3epsilon/delta/gamma/zeta chain
• Area di ricerca: Immunology