CD132 is a 64-70 kD type I transmembrane glycoprotein of the Ig superfamily, and is also known as common γ chain (γc) or IL-2 receptor γ subunit. It is expressed broadly on T- and B-lymphocytes, NK cells, monocytes, and granulocytes. CD132 is an essential component of cytokine receptors for IL-2, IL-4, IL-7, IL-9, IL-15, and IL-21. Ligand binding induces tyrosine phosphorylation and initiates signaling through a JAK/STAT pathway. CD132 mutation results in X-linked severe combined immune deficiency (XSCID).

Dettagli prodotto

• Codice: E-AB-F10150_100μg
• Marca: Elabscience
• Specie target: Mouse
• Host: Rat
• Concentrazione: ≥ 1 mg/mL
• Link: Apri link
• Stoccaggio: Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
• Isotipo: Rat IgG2b, κ
• Clonalità: Monoclonal
• Clone: 3E12
• Applicazione: FCM
• Simbolo target: CD132;Cytokine receptor common subunit gamma;IL-2 receptor subunit gamma;IL-2R subunit gamma;IL-2RG;Il2rg;Interleukin-2 receptor subunit gamma;gammaC;p64
• Area di ricerca: Immunology