CD132 is a 64-70 kD type I transmembrane glycoprotein of the Ig superfamily, and is also known as common γ chain (γc) or IL-2 receptor γ subunit. It is expressed broadly on T- and B-lymphocytes, NK cells, monocytes, and granulocytes. CD132 is an essential component of cytokine receptors for IL-2, IL-4, IL-7, IL-9, IL-15, and IL-21. Ligand binding induces tyrosine phosphorylation and initiates signaling through a JAK/STAT pathway. CD132 mutation results in X-linked severe combined immune deficiency (XSCID).

Codice: E-AB-F10150_1mg | Marca: Elabscience | Confezionamento: 1mg

Specie: MouseIsotipo: Rat IgG2b, κClone: 3E12

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Codice: E-AB-F10150_1mg
Marca: Elabscience
Specie target: Mouse
Host: Rat
Concentrazione: ≥ 1 mg/mL
Link: Apri link
Stoccaggio: Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
Isotipo: Rat IgG2b, κ
Clonalità: Monoclonal
Clone: 3E12
Applicazione: FCM
Simbolo target: CD132;Cytokine receptor common subunit gamma;IL-2 receptor subunit gamma;IL-2R subunit gamma;IL-2RG;Il2rg;Interleukin-2 receptor subunit gamma;gammaC;p64
Area di ricerca: Immunology

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