CD209B, also known as SIGN-R1, is a mouse C-type lectin receptor predominantly expressed on macrophages in the spleen marginal zone and lymph nodes medulla. CD209B is a mouse homolog of human CD209/DC-SIGN and is involved in innate immune response. CD209B mediates the recognition and uptake of pathogen products, such as lipopolysaccharides (LPS), pneumococcal polysaccharides, and dextrans. CD209B has been demonstrated to facilitate the clearance of encapsulated pneumococcus by directly binding to C1q and activating complement through an immunoglobulin independent pathway.

Codice: E-AB-F10220_25mg | Marca: Elabscience | Confezionamento: 25mg

Specie: MouseIsotipo: Armenian Hamster IgGClone: 22D1

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Codice: E-AB-F10220_25mg
Marca: Elabscience
Specie target: Mouse
Host: Armenian Hamster
Concentrazione: ≥ 1 mg/mL
Link: Apri link
Stoccaggio: Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
Isotipo: Armenian Hamster IgG
Clonalità: Monoclonal
Clone: 22D1
Applicazione: FCM
Simbolo target: CD209;CD209 antigen-like protein B;Cd209b;DC-SIGN-related protein 1;DC-SIGNR1;OtB7
Area di ricerca: 无

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