CD40 is a 48 kD type I transmembrane glycoprotein also known as Bp50. It is a member of the tumor necrosis factor receptor (TNFR) superfamily and is expressed on B cells, basal epithelial cells, macrophages, follicular dendritic cells, endothelial cells, and a subset of CD34+ hematopoietic progenitors. CD40 regulates B cell development/maturation, Ig isotype switching and, in combination with other signals such as IL-4, protects B cells from surface Ig-induced apoptosis and promotes proliferation. Interaction of CD40 with its ligand CD154 (gp39), which is expressed on activated T cells, is important in costimulation and immune regulation.

Codice: E-AB-F10280_25μg | Marca: Elabscience | Confezionamento: 25μg

Specie: MouseIsotipo: Rat IgG2a, κClone: FGK4.5/FGK45

Recombinant Mouse CD40 protein

Torna alla lista Apri link

Codice: E-AB-F10280_25μg
Marca: Elabscience
Specie target: Mouse
Host: Rat
Concentrazione: ≥ 1 mg/mL
Link: Apri link
Stoccaggio: Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
Isotipo: Rat IgG2a, κ
Clonalità: Monoclonal
Clone: FGK4.5/FGK45
Applicazione: FCM
Simbolo target: B-cell surface antigen CD40;Bp50;CD40;CD40L receptor;Cd40;Tnfrsf5;Tumor necrosis factor receptor superfamily member 5
Area di ricerca: Cell Biology;Costimulatory Molecules;Immunology;Neuroscience;Neuroscience Cell Markers

Scheda prodotto