CD120b is a 75 kD type I transmembrane protein, also known as Tumor Necrosis Factor Receptor Type II (TNFRII) or p75. It is expressed on a variety of cells at low levels; the expression is upregulated upon activation. This receptor binds both TNF-α and LT-α (also known as TNF-β). In association with TRAF1 and TRAF2, the receptor crosslinking induced by TNF-α or LT-α trimers is critical for signal transduction, leading to apoptosis, NF-kB activation, increased expression of proinflammatory genes, tumor necrosis, and cell differentiation depending on cell type and differentiation state.

Codice: E-AB-F10350_50mg | Marca: Elabscience | Confezionamento: 50mg

Specie: MouseIsotipo: Armenian Hamster IgGClone: TR75-54.7

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Codice: E-AB-F10350_50mg
Marca: Elabscience
Specie target: Mouse
Host: Armenian Hamster
Concentrazione: ≥ 1 mg/mL
Link: Apri link
Stoccaggio: Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
Isotipo: Armenian Hamster IgG
Clonalità: Monoclonal
Clone: TR75-54.7
Applicazione: FCM;Block
Simbolo target: CD120b;TNF-R2;TNF-RII;TNFR-II;Tnfrsf1b;Tumor necrosis factor receptor 2;Tumor necrosis factor receptor superfamily member 1B;p75;p80 TNF-alpha receptor
Area di ricerca: Immunology;Innate Immunity

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