CD29 is a 130 kD single chain type I glycoprotein also known as integrin β1, VLA-β chain, or gpIIa. It is broadly expressed on a majority of hematopoietic and non-hematopoietic cells, including leukocytes (although at low level on granulocytes), platelets, fibroblasts, endothelial cells, epithelial cells, and mast cells. CD29 is a member of the integrin family. It is non-covalently associated with integrin α1-α6 chains to form VLA-1 to VLA-6 molecules, respectively. Integrins, which include CD29, bind to several cell surface (e.g. VCAM-1, MadCAM-1) and extracellular matrix molecules. CD29 acts as a fibronectin receptor and is involved in a variety of cell-cell and cell-matrix interactions.

Dettagli prodotto

• Codice: E-AB-F10490_25mg
• Marca: Elabscience
• Specie target: Human
• Host: Mouse
• Concentrazione: ≥ 1 mg/mL
• Link: Apri link
• Stoccaggio: Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
• Isotipo: Mouse IgG1, κ
• Clonalità: Monoclonal
• Clone: TS2/16.2.1
• Applicazione: FCM
• Simbolo target: MSK;MDF;ITB;ITGB;Integrin β;CD29;FNRB;GPIIA;MDF2;MSK12;VLA-BETA;VLAB;Integrin beta 1;ITGB1;Integrin β1;Fibronectin receptor subunit beta;Integrin beta-1;ITB1;VLA-4 subunit beta;integrin &beta-1-1; gpIIa;antigen CD29 includes MDF2;beta 1 (fibronectin receptor;beta polypeptide;beta1 integrin;Glycoprotein IIa;GP IIa;Integrin;Integrin subunit beta 1;integrin VLA-4 beta subunit;MSK12);OTTHUMP00000019420;Very late activation protein;VLA BETA;VLAbeta
• Area di ricerca: Signal Transduction;Cancer;Metabolism;Neuroscience;Microbiology;Stem Cells;Developmental Biology