CD62L is a 74-95 kD glycoprotein also known as L-selectin, LECAM-1, Ly-22, LAM-1, and MEL-14. It is a member of the selectin family and is expressed on the majority of B and naive T cells, a subset of memory T cells, monocytes, granulocytes, most thymocytes, and a subset of NK cells. CD62L is important in lymphocyte homing to high endothelial venules (HEV) in peripheral lymph nodes and leukocyte 'rolling' on activated endothelium. CD62L also contributes to neutrophil emigration at inflammatory sites. CD62L is rapidly shed from lymphocytes and neutrophils upon cellular activation and the expression levels of CD62L (in conjunction with other markers) have been used to distinguish naive, effector, and memory T cells. CD62L has been reported to interact with CD34, GlyCAM-1, and MAdCAM-1.

Dettagli prodotto

• Codice: E-AB-F10510_50mg
• Marca: Elabscience
• Specie target: Human
• Host: Mouse
• Concentrazione: ≥ 1 mg/mL
• Link: Apri link
• Stoccaggio: Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
• Isotipo: Mouse IgG1, κ
• Clonalità: Monoclonal
• Clone: DREG56
• Applicazione: FCM
• Simbolo target: Leukocyte adhesion molecule;Leukocyte surface antigen Leu;Leukocyte-endothelial cell adhesion molecule;LECAM;LAM;LEU;SELL;CD62L;LAM1;LECAM1;LEU8;LNHR;LSEL;LYAM1;PLNHR;TQ1;CD62 antigen-like family member L;CD62antigen-likefamilymemberL;gp90-MEL;LAM-1;Leu-8;Leukocyte adhesion molecule 1;Leukocyte surface antigen Leu-8;Leukocyte-endothelial cell adhesion molecule 1;L-selectin;Ly22;Ly-22;Lyam-1;Lymph node homing receptor;Lymphnodehomingreceptor;6&apos- sulfated Lewis X-X; LECAM-1; LAM-1
• Area di ricerca: Cardiovascular;Immunology;Stem Cells