CD11b is a 170 kD glycoprotein also known as αM integrin, Mac-1 α subunit, Mol, CR3, and Ly-40. CD11b is a member of the integrin family, primarily expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b non-covalently associates with CD18 (β2 integrin) to form Mac-1. Mac-1 plays an important role in cell-cell interaction by binding its ligands ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, and fibrinogen.

Dettagli prodotto

• Codice: E-AB-F10810_25mg
• Marca: Elabscience
• Specie target: Human;Mouse
• Host: Rat
• Concentrazione: ≥ 1 mg/mL
• Link: https://www.elabscience.com/p-af/le_purified_rat_igg1,_κ_isotype_control[hrpn]-e_ab_f098230
• Stoccaggio: Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
• Isotipo: Rat IgG2b, κ
• Clonalità: Monoclonal
• Clone: M1/70
• Applicazione: FCM
• Simbolo target: CD11 antigen-like family member B;CD11b;CR-3 alpha chain;Integrin alpha-M;Itgam;Leukocyte adhesion receptor MO1
• Area di ricerca: Cell Adhesion;Cell Biology;Costimulatory Molecules;Immunology;Innate Immunity;Neuroscience;Neuroscience Cell Markers