CD41 is a 125/25 kD α subunit of the gpIIb/IIIa (CD41/CD61) complex. CD41 is a heterodimer composed of a heavy chain (gpIIbα) and light chain (gpIIbβ) linked by a single disulfide bond. It is a member of the integrin family primarily expressed on platelets and megakaryocytes. CD41 has been reported to be involved with platelet aggregation and platelet attachment to the ECM. CD41/CD61 complex acts as the receptor for fibrinogen, fibronectin, Von Willebrand factor and thrombin.

Dettagli prodotto

• Codice: E-AB-F10880_25mg
• Marca: Elabscience
• Specie target: Human
• Host: Mouse
• Concentrazione: ≥ 1 mg/mL
• Link: Apri link
• Stoccaggio: Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
• Isotipo: Mouse IgG1, κ
• Clonalità: Monoclonal
• Clone: HIP8
• Applicazione: FCM
• Simbolo target: HPA;PPP1R;ITGA2B;BDPLT16;BDPLT2;CD41;CD41B;GP2B;GPIIb;GT;GTA;HPA3;PPP1R93;GPalpha Iib;Integrin alpha-Iib;Platelet membrane glycoprotein Iib;ITGAB; &alpha-IIb integrin-n;BDPLT16;alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex;alpha subunit;antigen CD41;antigen CD41);form 2;Integrin;Integrin alpha 2b;Integrin alpha IIb;Integrin alpha-IIb light chain;integrin αⅡbβ3;ITA2B;platelet fibrinogen receptor;platelet glycoprotein IIb of IIb/IIIa complex;platelet specific antigen BAK
• Area di ricerca: Cardiovascular;Immunology;Signal Transduction;Stem Cells