CD183/CXCR3, also known as CXCR3, is a member of the C-X-C chemokine family, characterized by a pair of cysteine residues separated by a single amino acid. CXCR3 is a 38 kD seven pass transmembrane receptor coupled to G-protein. It mediates Ca2+ mobilization and chemotaxis in response to C-X-C chemokines, such as IP10 (CXCL10), MIG (CXCL9), I-TAC (CXCL11) and PF4 (CXCL4). CXCR3 is expressed primarily on activiated T lymphocytes, NK cells, and some epithelial cells and endothelial cells. It is not expressed on B cells, monocytes or granulocytes.

Dettagli prodotto

• Codice: E-AB-F11140_25mg
• Marca: Elabscience
• Specie target: Mouse
• Host: Armenian Hamster
• Concentrazione: ≥ 1 mg/mL
• Link: Apri link
• Stoccaggio: Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
• Isotipo: Armenian Hamster IgG
• Clonalità: Monoclonal
• Clone: CXCR3-173
• Applicazione: FCM;Block
• Simbolo target: C-X-C chemokine receptor type 3;CD183/CXCR3;CXC-R3;CXCR-3;Cxcr3;IP-10 receptor;Interferon-inducible protein 10 receptor
• Area di ricerca: Immunology;Innate Immunity