CD183/CXCR3, also known as CXCR3, is a member of the C-X-C chemokine family, characterized by a pair of cysteine residues separated by a single amino acid. CXCR3 is a 38 kD seven pass transmembrane receptor coupled to G-protein. It mediates Ca2+ mobilization and chemotaxis in response to C-X-C chemokines, such as IP10 (CXCL10), MIG (CXCL9), I-TAC (CXCL11) and PF4 (CXCL4). CXCR3 is expressed primarily on activiated T lymphocytes, NK cells, and some epithelial cells and endothelial cells. It is not expressed on B cells, monocytes or granulocytes.

Codice: E-AB-F11140_50mg | Marca: Elabscience | Confezionamento: 50mg

Specie: MouseIsotipo: Armenian Hamster IgGClone: CXCR3-173
Dettagli prodotto
  • Codice: E-AB-F11140_50mg
  • Marca: Elabscience
  • Specie target: Mouse
  • Host: Armenian Hamster
  • Concentrazione: ≥ 1 mg/mL
  • Link: Apri link
  • Stoccaggio: Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
  • Isotipo: Armenian Hamster IgG
  • Clonalità: Monoclonal
  • Clone: CXCR3-173
  • Applicazione: FCM;Block
  • Simbolo target: C-X-C chemokine receptor type 3;CD183/CXCR3;CXC-R3;CXCR-3;Cxcr3;IP-10 receptor;Interferon-inducible protein 10 receptor
  • Area di ricerca: Immunology;Innate Immunity