Functional IL-2 receptors can exist in two affinity states on cell surfaces, the high affinity complex consisting of heterotrimers of the alpha, beta, and gamma chains and the intermediate affinity complex comprising heterodimers of the beta and gamma chains. Individual beta chains and alpha chains exhibit low affinity IL-2 binding, and the gamma chain alone does not bind IL-2. In addition to their involvement in IL-2 mediated signal transduction, both the beta chain and gamma chain have been shown to be required for IL-15 mediated signaling. IL-2 R beta is a member of the cytokine receptor superfamily.

Dettagli prodotto

• Codice: E-AB-F11510_100μg
• Marca: Elabscience
• Specie target: Human
• Host: Mouse
• Concentrazione: ≥ 1 mg/mL
• Link: Apri link
• Stoccaggio: Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
• Isotipo: Mouse IgG1, κ
• Clonalità: Monoclonal
• Clone: TU27
• Applicazione: FCM
• Simbolo target: P70;IL2RB;CD122;IL15RB;P70-75;IL-2Rβ;p75;IL-2RB;Interleukin-2 receptor subunit beta;IL-2 receptor subunit beta;IL-2R subunit beta;High affinity IL-2 receptor subunit beta;Interleukin-15 receptor subunit beta;p70-75 (p75);IL-2RβCD122 antigen;High affinity IL 2 receptor beta subunit;High affinity IL 2 receptor subunit beta;IL2 receptor;Interleukin 2 receptor beta;interleukin 2 receptor subunit beta;P70 75;P7075
• Area di ricerca: Immunology;Signal Transduction;Stem Cells