The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. Signals mediated by this receptor regulate T cell homeostasis in lymph nodes, and may also function in the activation and polarization of T cells, and in chronic inflammation pathogenesis. Alternative splicing of this gene results in multiple transcript variants.

Codice: E-AB-F11590_100μg | Marca: Elabscience | Confezionamento: 100μg

Specie: HumanIsotipo: Mouse IgG2a, κClone: G043H7
Note

Recombinant Human CD197 protein

Dettagli prodotto
  • Codice: E-AB-F11590_100μg
  • Marca: Elabscience
  • Specie target: Human
  • Host: Mouse
  • Concentrazione: ≥ 1 mg/mL
  • Link: Apri link
  • Stoccaggio: Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
  • Isotipo: Mouse IgG2a, κ
  • Clonalità: Monoclonal
  • Clone: G043H7
  • Applicazione: FCM
  • Simbolo target: EBI;CDw;BLR;EVI;CMKBR;CC-CKR;CCR;CCR7;BLR2;CC-CKR-7;CCR-7;CD197;CDw197;CMKBR7;EBI1;EVI1; EBI-1; BLR-2; CMKBR7
  • Area di ricerca: Immunology;Signal Transduction