T cells require a signal induced by the engagement of the T cell receptor and a “co‑stimulatory” signal(s) through distinct T cell surface molecules for optimal T cell activation and tolerance. Members of the B7 superfamily of counter-receptors were identified by their ability to interact with co‑stimulatory molecules found on the surface of T cells. Members of the B7 superfamily include B7-1 (CD80), B7-2 (CD86), B7-H1 (PD-L1), B7-H2 (B7RP-1), B7-H3, and PD-L2 (B7-DC).

Dettagli prodotto

• Codice: E-AB-F11750_50mg
• Marca: Elabscience
• Specie target: Human
• Host: Mouse
• Concentrazione: ≥ 1 mg/mL
• Link: Apri link
• Stoccaggio: Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
• Isotipo: Mouse IgG2a, κ
• Clonalità: Monoclonal
• Clone: 24F.10C12
• Applicazione: FCM
• Simbolo target: PDL;PD-L;PD-1 ligand;PDCD1 ligand;Programmed death ligand;Programmed cell death 1 ligand;PDCD1L;bA574F;PDCD1LG;B7DC;Btdc;CD273;PD-L2;PDCD1L2;PDL2;bA574F11.2;PDCD1LG2;B7-DC;Butyrophilin B7-DC;Programmed cell death 1 ligand 2;PD-1 ligand 2;PDCD1 ligand 2;Programmed death ligand 2; PDL2; PD-L2;B7 dendritic cell molecule;Butyrophilin B7 DC;Butyrophilin B7DC;CD 273;CD273 antigen;MGC142238;MGC142240;PD 1 ligand 2;PD L2;PD1 ligand 2;PD1L2;PDCD 1 ligand 2;PDL 2
• Area di ricerca: Immunology