Endoglin (ENG, CD105) is a homodimeric cell membrane glycoprotein of 180 kDa, composed of disulphide-linked subunits of 90-95 kDa. Endoglin is a proliferation-associated and hypoxia-inducible protein mainly expressed on vascular endothelial cells. It acts as an accessory receptor for transforming growth factor beta (TFG-β) and is involved in vascular development and remodelling. The important role of Endoglin in angiogenesis and in tumor progression makes it an ideal target for antiangiogenic therapy and a good marker for tumor prognosis.

Dettagli prodotto

• Codice: E-AB-F12330_25μg
• Marca: Elabscience
• Specie target: Mouse
• Host: Rat
• Concentrazione: ≥ 1 mg/mL
• Link: https://www.elabscience.com/p-af/le_purified_anti_mouse/rat_cd29_antibody[hmβ1_1]-e_ab_f13090
• Stoccaggio: Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
• Isotipo: Rat IgG2a, κ
• Clonalità: Monoclonal
• Clone: MJ7/18
• Applicazione: FCM
• Simbolo target: HHT;ORW1;AI528660;AI662476;CD105;END;Endo;Endoglin;HHT1;ORW;S-endoglin;Edg;Eng;END;HHT1;ORW;ORW1;CD 105;CD105 antigen;EGLN;FLJ41744;Osler Rendu Weber syndrome 1;RP11 228B15.2;SN6