CD16 is a 60 kD highly glycosylated protein. It is a member of the Ig superfamily and is also known as B7-1, B7, and Ly-53. CD16 is constitutively expressed on dendritic cells and monocytes/macrophages, and inducibly expressed on activated B and T cells. The ligation of CD28 on T cells with CD16 and CD86 (B7-2) on antigen presenting cells (such as dendritic cells, macrophages, and B cells) elicits co-stimulation of T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD16 appears to be expressed later in the immune response than CD86. CD16 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.

Dettagli prodotto

• Codice: E-AB-F12360_5mg
• Marca: Elabscience
• Specie target: Human
• Host: Mouse
• Concentrazione: ≥ 1 mg/mL
• Link: Apri link
• Stoccaggio: Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
• Isotipo: Mouse IgG1, κ
• Clonalità: Monoclonal
• Clone: 3G8
• Applicazione: FCM;Block
• Simbolo target: FCR;IMD;FCG;Fcgr;IGFR;IgG Fc Receptor III;CD16;CD16A;FCG3;FCGR3;FCGRIII;FCR-10;FCRIII;FCRIIIA;IGFR3;IMD20;FCGR3A;CD16a Antigen;Fc-Gamma RIII;Fc-gamma RIIIa;Fc-Gamma RIII-Alpha;IgG Fc Receptor III-2;Low Affinity Immunoglobulin Gamma Fc Region Receptor III-A;Fc&gamma-RIIIA-A; CD16a;CD 16;CD 16a;CD16B;CD16b antigen;Fc fragment of IgG;Fc fragment of IgG low affinity IIIa receptor;Fc fragment of IgG low affinity IIIa receptor (CD16);Fc fragment of IgG receptor IIIa;Fc gamma R3;Fc gamma receptor III 2 (CD 16);Fc gamma receptor III A;Fc gamma receptor IIIA;Fc gamma receptor IIIb (CD 16);Fc gamma RIII;Fc gamma RIII alpha;Fc gamma RIII beta;Fc gamma RIIIa;Fc gamma RIIIb;Fc of IgG;FCG 3;FCG3A;Fc-gamma receptor III2 (CD 16);Fc-gamma receptor III2 (CD16);Fc-gamma receptor IIIb (CD16);FCgammaRIIIA;FCGR 3;FCGR 3A;FCGR3A protein;FCGRIII-2;FcR 10;FcR10;IGFR 3;IgG Fc receptor III 1;IgG Fc receptor III 2;immunoglobulin G Fc receptor III;immunoglobulin G Fc receptor III-2;low affinity III;low affinity IIIa;Low affinity IIIa receptor;low affinity IIIb;Low affinity immunoglobulin gamma Fc region receptor III A;Low affinity immunoglobulin gamma Fc region receptor IIIB;neutrophil-specific antigen NA;receptor (CD16);receptor (CD16a);receptor (CD16b);receptor for;receptor for (CD16);FCG;FCR;Fcgr;IgG Fc receptor III;IGFR;FCGR3B;CD16;CD16b;FCG3;FCGR3;FCR-10;FCRIII;FCRIIIb;CD16b and FCGR3B;CD16b and FCGR4B;CD16b and FCGR5B;CD16b and FCGR6B;Fc-gamma RIII-beta;IgG Fc receptor III-1;Low affinity immunoglobulin gamma Fc region receptor III-B;IGFR3;Fc&gamma-RIIIB-B;CD16A;Fc fragment of IgG receptor IIIb;FCGR3A
• Area di ricerca: Immunology;Stem Cells;Immunology