This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.

Dettagli prodotto

• Codice: E-AB-F12690_5mg
• Marca: Elabscience
• Specie target: Human
• Host: Mouse
• Concentrazione: ≥ 1 mg/mL
• Link: Apri link
• Stoccaggio: Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
• Isotipo: Mouse IgG2b, κ
• Clonalità: Monoclonal
• Clone: IT2.2
• Applicazione: FCM
• Simbolo target: LAB;ETC;FUN;CTLA-4 Counter-Receptor B;Early T-cell costimulatory molecule;CD28LG;B7-2;B7.2;B70;CD28LG2;LAB72;CD86;Activation B7-2 antigen;BU63;CTLA-4 Counter-Receptor B7.2;Early T-cell costimulatory molecule 1;ETC-1;FUN-1;T-lymphocyte activation antigen CD86; B7-2;Activation B7-2 antigen 3;B7 2;B72 antigen;B-lymphocyte activation antigen B7-2;B-lymphocyte activation antigen B7-2 2;CD28 antigen ligand 2;CD28 antigen ligand 2 2;Cd28l2;CD86 antigen;CD86 molecule;CLS1;CTLA-4 counter-receptor B7.2 2;FUN 1;Ly58;Ly-58;MB7;MB7-2;Membrane glycoprotein;MGC34413;TS/A-2
• Area di ricerca: Immunology;Microbiology;Stem Cells;Kits;Lysates;Other