Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles. Two transcript variants encoding different isoforms have been found for this gene.

Dettagli prodotto

• Codice: E-AB-F14860_1mg
• Marca: Elabscience
• Specie target: Human
• Host: Mouse
• Concentrazione: ≥ 1 mg/mL
• Link: Apri link
• Stoccaggio: Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
• Isotipo: Mouse IgG1, κ
• Clonalità: Monoclonal
• Clone: 3.9
• Applicazione: FCM
• Simbolo target: SLEB;Leukocyte adhesion receptor p150+;ITGAX;CD11C;SLEB6;CD11 antigen-like family member C;Integrin alpha-X;Leukocyte adhesion receptor p150+95;p150-95; CR4; integrin &alpha-X-X
• Area di ricerca: Signal Transduction;Immunology;Stem Cells