CD10, also known as common acute lymphoblastic leukemia antigen (CALLA), which is expressed in bone marrow hematopoietic stem cells (including neutrophils), follicular centroblasts, some mature B lymphocytes and parafollicular T lymphocytes. CD10 is also found in the upper layer of intestinal brush border cells, liver cholangiocarcinoma,glomeruli and renal tubular cells,alveolar cells, myoepithelial cells, breast, sweat gland,salivary gland,prostate cells and a small number of fibroblasts. CD10 is expressed in most acute lymphoblastic leukemia, follicular lymphoma and Burkitt's lymphoma. CD10 can be specifically used for
the identification and classification of B-cell leukemia/lymphoma and other tumors, such as hepatocellular carcinoma and renal cell carcinoma.