Cysteine Protease ATG4A (ATG4A) is a cytoplasmic protein that belongs to the peptidase C54 family. ATG4A is widely expressed in many tissues at a low level, but the highest expression is observed in skeletal muscle and brain. ATG4A is a cysteine protease required for autophagy; it cleaves the C-terminal part of MAP1LC3, GABARAPL2 or GABARAP. ATG4A is inhibited by N-ethylmaleimide. It is suggested that ATG4A has a significant role in suppressing various cancers.

Dettagli prodotto

• Codice: PKSH032099_10μg
• Marca: Elabscience
• Specie target: Human
• Host: E.coli
• Confezionamento: Supplied as a 0.2 μm filtered solution of PBS, pH7.4.
• Link: Apri link
• Stoccaggio: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
• Simbolo target: ATG4A
• Ig target: APG4A;ATG4A;AUT-Like 2 Cysteine Endopeptidase;AUTL2;Autophagin-2;Autophagy-Related Cysteine Endopeptidase 2;Autophagy-Related Protein 4 Homolog A;Cysteine Protease ATG4A;hAPG4A
• Area di ricerca: Signal Transduction;Cell biology;Cardiovascular;Cancer;metabolism;