Stromal derived factors (SDFs) are a loosely defined group of molecules that are generated by stromal cells. Two of the stromal derived factors, SDF-1 and SDF-4 belong to the chemokine family. Other SDFs, such as SDF-2 and SDF-5 are not well defined and their biological functions are less known. SDF-2 is first isolated from themousestromal cell lineST2 as asecretory protein. The amino acid sequence deduced from themurineclone and thehumanhomologare conserved more than 92 %, and the aa sequence of SDF-2 shows similarity to those ofyeastdolichyl phosphate-D-mannose, protein mannosyltransferases. SDF-1 and its receptor are strongly indicated in the progression of various cancers including breast cancer. SDF-2, SDF2-L1, SDF-4, and SDF-5 are ubiquitously expressed in various cancer cell lines and SDF-2, SDF-4 and SDF-5 are expressed in mammary tissues. These SDFs have prognostic value and warrant further investigation in their biological functions and clinical value.

Codice: PKSM040783_100μg | Marca: Elabscience | Confezionamento: 100μg

Specie: Mouse

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Codice: PKSM040783_100μg
Marca: Elabscience
Specie target: Mouse
Host: Baculovirus-Insect Cells
Confezionamento: Lyophilized from sterile 20mM Tris, 500mM NaCl, pH 8.0<br/>Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.<br/>Please refer to the specific buffer information in the printed manual.
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Stoccaggio: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Ig target: AI853825

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