Protein S100-A8(Mrp8) contains 2 EF-hand domains and belongs to the S-100 family. Mrp8 binds two calcium ions per molecule with an affinity similar to that of the S-100 proteins. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. It may function in the inhibition of casein kinase and as a cytokine. Altered expression of this protein is associated with the disease cystic fibrosis.

Dettagli prodotto

• Codice: PKSM041133_10μg
• Marca: Elabscience
• Specie target: Mouse
• Host: E.coli
• Confezionamento: Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, pH 8.0.<br/>Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.<br/>Please refer to the specific buffer information in the printed manual.
• Link: Apri link
• Stoccaggio: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
• Simbolo target: S100A8;CAGA
• Ig target: 60B8Ag;AI323541;B8Ag;CFAg;CP;Caga;Calgranulin-A;Chemotactic cytokine CP-10;Leukocyte L1 complex light chain;MRP-8;Migration inhibitory factor-related protein 8;Mrp8;Pro-inflammatory S100 cytokine;Protein S100-A8;S100 calcium-binding protein A8;S100a8