MTF2, also named as Metal-response element-binding transcription factor 2, is a 593 amino acid protein. It exists several isoforms and the range of the molecular weight of isoforms are about 55-60 kDa and 29 kDa. MTF2 contains 2 PHD-type zinc fingers and belongs to the Polycomblike family. MTF2 acts by binding to H3K36me3, a mark for transcriptional activation, and recruiting the PRC2 complex, leading to enhance PRC2 H3K27me3 methylation activity and regulates the transcriptional networks during embryonic stem cell self-renewal and differentiation.

Dettagli prodotto

• Codice: AN302036L_100μL
• Marca: Elabscience
• Specie target: Human;Mouse
• Host: Rabbit
• Concentrazione: 1 mg/mL
• Link: Apri link
• Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
• Isotipo: IgG,κ
• Clonalità: Monoclonal;Recombinant
• Clone: A756
• Coniugazione: Unconjugated
• Applicazione: WB
• Diluizione: WB 1:1000
• Simbolo target: MTF2
• Ig target: PCL;MTF;dJ976O;MTF2;M96;PCL2;TDRD19A;dJ976O13.2;hPCl2;metal regulatory transcription factor 2;Metal response element binding transcription factor 2;metal-response element DNA-binding protein M96;polycomb-like 2;polycomb-like protein 2;Putative DNA binding protein;RP5 976O13.1;RP5-976O13.1;tudor domain containing 19A
• Area di ricerca: Epigenetics and Nuclear Signaling