This gene encodes a transcriptional coregulator that binds to and enhances the activity of members of the nuclear receptor families, thyroid hormone receptors and retinoid X receptors. This protein also acts as a corepressor of NF-kappaB-dependent signaling. This protein induces apoptosis in breast cancer cells through a caspase 2-mediated signaling pathway. This protein is also a component of the centromere-specific histone H3 variant nucleosome associated complex (CENP-NAC) and may be involved in mitotic progression by recruiting the histone H3 variant CENP-A to the centromere. Alternate splicing results in multiple transcript variants.

Codice: E-AB-10402_200μL | Marca: Elabscience | Confezionamento: 200μL

Specie: HumanIsotipo: IgGConiugazione: Unconjugated

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Codice: E-AB-10402_200μL
Marca: Elabscience
Specie target: Human
Host: Rabbit
Concentrazione: 0.7 mg/mL
Link: Apri link
Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
Isotipo: IgG
Clonalità: Polyclonal
Coniugazione: Unconjugated
Applicazione: IHC
Diluizione: IHC 1:50-1:200
Simbolo target: ITGB3BP
Ig target: Beta 3 endonexin;Beta3 endonexin;Beta3 endonexin long form;CENP R;CENPR;CENPR;Centromere protein R;endonexin;Beta-3;HSU37139;Integrin beta 3 binding protein (beta3-endonexin);Integrin beta 3 binding protein;NRIF 3;NRIF3;Nuclear receptor interacting factor 3;TAP 20;TAP20
Area di ricerca: Epigenetics and Nuclear Signaling;Signal Transduction

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