The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronaviruses SARS and HCoV-NL63.

Dettagli prodotto

• Codice: E-AB-12224_20μL
• Marca: Elabscience
• Specie target: Human;Mouse;Rat
• Host: Rabbit
• Concentrazione: 0.5 mg/mL
• Link: Apri link
• Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
• Isotipo: IgG
• Clonalità: Polyclonal
• Coniugazione: Unconjugated
• Applicazione: IHC
• Diluizione: IHC 1:100-1:300
• Simbolo target: ACE2
• Ig target: ACE 2;ACE related carboxypeptidase;ACE-related carboxypeptidase;ACE2;ACE2;ACEH;Angiotensin converting enzyme 2;Angiotensin converting enzyme homolog;Angiotensin converting enzyme like protein;Angiotensin I Converting Enzyme (peptidyl dipeptidase A) 2;Angiotensin I converting enzyme 2;Angiotensin-converting enzyme homolog;DKFZP434A014;EC 3.4.17;metalloprotease MPROT 15;Metalloprotease MPROT15;OTTHUMP00000022963;Processed angiotensin-converting enzyme 2
• Area di ricerca: Cancer;Cell Biology;Cardiovascular