The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

Dettagli prodotto

• Codice: E-AB-12968_20μL
• Marca: Elabscience
• Specie target: Human;Mouse;Rat
• Host: Rabbit
• Concentrazione: 0.5 mg/mL
• Link: Apri link
• Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
• Isotipo: IgG
• Clonalità: Polyclonal
• Coniugazione: Unconjugated
• Applicazione: IHC
• Diluizione: IHC 1:100-1:300
• Simbolo target: PRKAA1
• Ig target: 5 AMP activated protein kinase alpha 1catalytic subunit;5 AMP activated protein kinase catalytic alpha 1 chain;5' AMP activated protein kinase catalytic subunit alpha 1;5'-AMP-activated protein kinase catalytic subunit alpha-1;AAPK1;AAPK1;ACACA kinase;acetyl CoA carboxylase kinase;AI194361;AI450832;AL024255;AMP -activate kinase alpha 1 subunit;AMP-activated protein kinase;catalytic;alpha -1;AMPK 1;AMPK alpha 1;AMPK alpha 1 chain;AMPK;AMPK subunit alpha-1;AMPK1;AMPKa1;AMPKalpha1;C130083N04Rik;cb116;EC 2.7.11.1;HMG CoA reductase kinase;HMGCR kinase;hormone sensitive lipase kinase;Hydroxymethylglutaryl CoA reductase kinase;im:7154392;kinase AMPK alpha1;MGC33776;MGC57364;OTTHUMP00000161795;OTTHUMP00000161796;PRKAA 1;PRKAA1;Protein kinase AMP activated alpha 1 catalytic subunit;SNF1-like protein AMPK;SNF1A;Tau protein kinase PRKAA1;wu:fa94c10
• Area di ricerca: Cancer;Cardiovascular;Metabolism;Neuroscience;Signal Transduction