The protein encoded by this gene contains SAM, ARF-GAP, RHO-GAP, ankyrin repeat, RAS-associating, and pleckstrin homology (PH) domains. In vitro, this protein displays RHO-GAP and phosphatidylinositol (3,4,5) trisphosphate (PIP3)-dependent ARF-GAP activity. The encoded protein associates with the Golgi, and the ARF-GAP activity mediates changes in the Golgi and the formation of filopodia. It is thought to regulate the cell-specific trafficking of a receptor protein involved in apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene.

Codice: E-AB-12988_60μL | Marca: Elabscience | Confezionamento: 60μL

Specie: Human;MouseIsotipo: IgGConiugazione: Unconjugated
Dettagli prodotto
  • Codice: E-AB-12988_60μL
  • Marca: Elabscience
  • Specie target: Human;Mouse
  • Host: Rabbit
  • Concentrazione: 0.2 mg/mL
  • Link: Apri link
  • Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
  • Isotipo: IgG
  • Clonalità: Polyclonal
  • Coniugazione: Unconjugated
  • Applicazione: IHC
  • Diluizione: IHC 1:50-1:200
  • Simbolo target: ARAP1
  • Ig target: 2410002L19Rik;ANK repeat and PH domain-containing protein 1;ARAP 1;Arap1;ARAP1;Arf GAP Rho GAP ankyrin repeat and pleckstrin homology domains containing protein 1;Arf GAP Rho GAP ankyrin repeat and pleckstrin homology domain containing protein 1;Arf-GAP with Rho-GAP domain;CENT D2;Centaurin delta 2;Centaurin delta2;Centaurin-delta-2;CENTD 2;CENTD2;Cnt d2;Cnt-d2;Cntd2;KIAA0782;MGC176140;mKIAA0782
  • Area di ricerca: Signal Transduction