May act in regulation of cell growth and transformation by interacting with nonreceptor tyrosine kinases ABL1 and/or ABL2. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex. Regulates ABL1/c-Abl-mediated phosphorylation of MENA. As component of the WAVE1 complex, required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes.

Codice: E-AB-18253_120μL | Marca: Elabscience | Confezionamento: 120μL

Specie: HumanIsotipo: IgGConiugazione: Unconjugated

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Codice: E-AB-18253_120μL
Marca: Elabscience
Specie target: Human
Host: Rabbit
Concentrazione: 0.78 mg/mL
Link: Apri link
Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
Isotipo: IgG
Clonalità: Polyclonal
Coniugazione: Unconjugated
Applicazione: IHC
Diluizione: IHC 1:50-1:100
Simbolo target: ABI2
Ig target: Abelson interactor 2;ABI 2;Abi-2;ABI2;ABI2;ABI2B;Abl binding protein 3;Abl interacting protein 1 (SH3 containing protein);Abl interactor 2;Abl interactor protein 2b;Abl-binding protein 3;AblBP3;AIP 1;Arg binding protein 1;Arg protein tyrosine kinase binding protein;Arg-binding protein 1;ArgBP1;ARGBPIA;ArgBPIB;OTTHUMP00000163783;OTTHUMP00000163784;OTTHUMP00000206182;OTTHUMP00000206183;OTTHUMP00000206184;OTTHUMP00000206185;SSH3BP2
Area di ricerca: Cancer

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