Involved in the inhibition of the inflammatory response. Acts as a negative regulator of the Toll-like receptors (TLRs)-mediated inflammatory innate response by stimulating the tumor necrosis factor alpha-induced protein TNFAIP3 expression via reactive oxygen species (ROS) in LPS-tolerized macrophages. Involved in antimicrobial response of innate immune cells; ACOD1-mediated itaconic acid production contributes to the antimicrobial activity of macrophages. Plays a role in the embryo implantation.

Codice: E-AB-19833_120μL | Marca: Elabscience | Confezionamento: 120μL

Specie: Human;MouseIsotipo: IgGConiugazione: Unconjugated

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Codice: E-AB-19833_120μL
Marca: Elabscience
Specie target: Human;Mouse
Host: Rabbit
Concentrazione: 1.32 mg/mL
Link: Apri link
Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
Isotipo: IgG
Clonalità: Polyclonal
Coniugazione: Unconjugated
Applicazione: WB
Diluizione: WB 1:500-1:2000
Simbolo target: ACOD1
Ig target: ACOD1;Aconitate decarboxylase 1;Aconitate decarboxylase;CAD;Cis aconitate decarboxylase;Immune responsive gene 1 protein homolog;Immune-responsive gene 1 protein homolog;Immunoresponsive 1 homolog (mouse);Irg1;IRG1;OC116;OPTB1;TCTIRC7
Area di ricerca: Metabolism;Immunology;Signal transduction

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