ITGA2B encodes integrin alpha chain 2b. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 2b undergoes post-translational cleavage to yield disulfide-linked light and heavy chains that join with beta 3 to form a fibronectin receptor expressed in platelets that plays a crucial role in coagulation. Mutations that interfere with this role result in thrombasthenia. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling.

Dettagli prodotto

• Codice: E-AB-22101_60μL
• Marca: Elabscience
• Specie target: Human
• Host: Mouse
• Concentrazione: 1 mg/mL
• Link: Apri link
• Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
• Isotipo: IgG
• Clonalità: Monoclonal
• Clone: Clone:5D1
• Coniugazione: Unconjugated
• Applicazione: IHC-p
• Diluizione: IHC 1:50-200
• Simbolo target: CD41
• Ig target: antigen CD41;BDPLT16;BDPLT2;CD41;CD41B;form 2;GP2B;GPalpha IIb;GPIIb;GT;GTA;HPA3;Integrin alpha 2b;Integrin alpha IIb;Integrin alpha-IIb light chain;Integrin;alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex;antigen CD41);ITA2B;Itga2b;ITGAB;platelet fibrinogen receptor;alpha subunit;platelet glycoprotein IIb of IIb/IIIa complex;Platelet membrane glycoprotein IIb;platelet specific antigen BAK;PPP1R93
• Area di ricerca: Cancer;Cardiovascular;Immunology;Signal Transduction;Stem Cells