This gene encodes a pleckstrin homology domain-containing adapter protein. The encoded protein is localized to the plasma membrane where it specifically binds phosphatidylinositol 3,4-bisphosphate. This protein may be involved in the formation of signaling complexes in the plasma membrane. Polymorphisms in this gene are associated with age-related macular degeneration. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 5.

Dettagli prodotto

• Codice: E-AB-52629_200μL
• Marca: Elabscience
• Specie target: Human
• Host: Rabbit
• Concentrazione: 1.08 mg/mL
• Link: Apri link
• Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
• Isotipo: IgG
• Clonalità: Polyclonal
• Coniugazione: Unconjugated
• Applicazione: IHC
• Diluizione: IHC 1:30-1:150
• Simbolo target: PLEKHA1
• Ig target: OTTHUMP00000020651;PH domain containing family A member 1;PH domain-containing family A member 1;PKHA1;Pleckstrin homology domain containing A1;Pleckstrin homology domain containing family A member 1;Pleckstrin homology domain containing; family A (phosphoinositide binding specific) member;Pleckstrin homology domain-containing family A member 1;PLEKHA1;Tandem PH domain containing protein 1;Tandem PH domain-containing protein 1;TAPP 1;TAPP-1;TAPP1
• Area di ricerca: Signal transduction