Tissue specific transplantation antigen P35B is a NADP(H)-binding protein. It catalyze the two-step epimerase and the reductase reactions in GDP-D-mannose metabolism, converting GDP-4-keto-6-D-deoxymannose to GDP-L-fucose. GDP-L-fucose is the substrate of several fucosyltransferases involved in the expression of many glycoconjugates, including blood group ABH antigens and developmental adhesion antigens. Mutations in this gene may cause leukocyte adhesion deficiency, type II.

Dettagli prodotto

• Codice: E-AB-53147_120μL
• Marca: Elabscience
• Specie target: Human;Mouse
• Host: Rabbit
• Concentrazione: 1.44 mg/mL
• Link: Apri link
• Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
• Isotipo: IgG
• Clonalità: Polyclonal
• Coniugazione: Unconjugated
• Applicazione: IHC
• Diluizione: IHC 1:50-1:200
• Simbolo target: TSTA3
• Ig target: 3 5 epimerase/4 reductase;5-epimerase-4-reductase;anti TSTA3;EC 1.1.1.271;FCL;FX;GDP 4 keto 6 deoxy D mannose 3 5 epimerase 4 reductase;GDP 4 keto 6 deoxy D mannose epimerase reductase;GDP L fucose synthase;GDP-4-keto-6-deoxy-D-mannose-3;GDP-L-fucose synthase;P35B;Protein FX;Red cell NADP(H) binding protein;Red cell NADP(H)-binding protein;SDR4E1;Short chain dehydrogenase/reductase family 4E member 1;Short-chain dehydrogenase/reductase family 4E member 1;Tissue specific transplantation antigen 3;Tissue specific transplantation antigen P35B;TSTA3;TSTA3
• Area di ricerca: Metabolism;Signal transduction