This gene encodes a member of the PPM family of Mn2+/Mg2+-dependent protein phosphatases. The encoded protein, essential for cell survival and development, is targeted to the mitochondria where it plays a key role in regulation of the mitochondrial permeability transition pore.PPM1K (Protein Phosphatase, Mg2+/Mn2+ Dependent 1K) is a Protein Coding gene. Diseases associated with PPM1K include Maple Syrup Urine Disease, Mild Variant and Intermediate Maple Syrup Urine Disease. Among its related pathways are Valine, leucine and isoleucine degradation and Viral mRNA Translation. GO annotations related to this gene include protein serine/threonine phosphatase activity. An important paralog of this gene is PPM1E.

Dettagli prodotto

• Codice: E-AB-53177_200μL
• Marca: Elabscience
• Specie target: Human;Mouse
• Host: Rabbit
• Concentrazione: 0.78 mg/mL
• Link: Apri link
• Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
• Isotipo: IgG
• Clonalità: Polyclonal
• Coniugazione: Unconjugated
• Applicazione: IHC
• Diluizione: IHC 1:50-1:100
• Simbolo target: PPM1K
• Ig target: BDP;mitochondrial;MSUDMV;PP2C domain containing protein phosphatase 1K;PP2C domain-containing protein phosphatase 1K;PP2C kappa;PP2C like mitochondrial protein;PP2C type mitochondrial phosphoprotein phosphatase;PP2C-kappa;PP2C-like mitochondrial protein;PP2C-type mitochondrial phosphoprotein phosphatase;PP2Ckappa;PP2CM;PPM1K;PPM1K;Protein phosphatase 1K;Protein phosphatase 1K;mitochondrial;Protein phosphatase 2C isoform kappa;Protein phosphatase Mg2+/Mn2+ dependent 1K;PTMP;UG0882E07
• Area di ricerca: Cancer;Cardiovascular;Metabolism;Signal Transduction;Tags and Cell Markers