This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. This protein functions as a transcriptional repressor and may regulate tissue specific expression of dopamine receptor D1. Mutations in this gene cause holoprosencephaly type 5. Holoprosencephaly is the most common structural anomaly of the human brain. A polyhistidine tract polymorphism in this gene may be associated with increased risk of neural tube defects. This gene is closely linked to a gene encoding zinc finger protein of the cerebellum 5, a related family member on chromosome 13.

Dettagli prodotto

• Codice: E-AB-53238_60μL
• Marca: Elabscience
• Specie target: Human;Mouse
• Host: Rabbit
• Concentrazione: 2 mg/mL
• Link: Apri link
• Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
• Isotipo: IgG
• Clonalità: Polyclonal
• Coniugazione: Unconjugated
• Applicazione: IHC
• Diluizione: IHC 1:50-1:200
• Simbolo target: ZIC2  
• Ig target: HPE 5;HPE5;Odd paired homolog Drosophila;Zic 2;Zic family member 2 (odd paired Drosophila homolog);Zic family member 2;ZIC2;ZIC2;Zinc finger protein of the cerebellum 2;Zinc finger protein ZIC 2;Zinc finger protein Zic2
• Area di ricerca: Epigenetics and Nuclear Signaling;Neuroscience;Signal Transduction