This gene encodes a member of the IQGAP family. The protein contains four IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. It interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. Expression of the protein is upregulated by gene amplification in two gastric cancer cell lines.
Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
Isotipo: IgG
Clonalità: Polyclonal
Coniugazione: Unconjugated
Applicazione: WB;IHC
Diluizione: WB 1:500-1:2000;IHC 1:25-1:100
Simbolo target: IQGAP1
Ig target: HUMORFA01;IQ motif containing GTPase activating protein 1;IQGA1;Iqgap1;KIAA0051;p195;Ras GTPase activating like protein 1;Ras GTPase-activating-like protein IQGAP1;RasGAP-like with IQ motifs;SAR1
Area di ricerca:Cancer;Signal Transduction
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