This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternative splicing results in multiple transcript variants.

Dettagli prodotto

• Codice: E-AB-70155_200μL
• Marca: Elabscience
• Specie target: Human;Mouse;Rat
• Host: Rabbit
• Concentrazione: 1 mg/mL
• Link: Apri link
• Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
• Isotipo: IgG
• Clonalità: Polyclonal
• Coniugazione: Unconjugated
• Applicazione: WB
• Diluizione: WB 1:500-1:2000
• Simbolo target: NTRK2
• Ig target: AI848316;BDNF tropomyosine receptor kinase B;BDNF/NT 3 growth factors receptor;BDNF/NT-3 growth factors receptor;Brain derived neurotrophic factor receptor;C030027L06Rik;EC 2.7.10.1;GP145 TrkB;GP145-TrkB;GP145-TrkB/GP95-TrkB;GP95 TrkB;Neurotrophic receptor tyrosine kinase 2;Neurotrophic tyrosine kinase receptor type 2;Neurotrophin receptor tyrosine kinase type 2;NTRK 2;Ntrk2;NTRK2;Obesity;hyperphagia;and developmental delay;included;RATTRKB1;Tkrb;Trk B;Trk-B;TRKB;TrkB tyrosine kinase;TRKB1;Tropomyosin related kinase B;tyrosine kinase receptor B;Tyrosine receptor kinase B
• Area di ricerca: Cancer;Metabolism;Neuroscience