The protein encoded by this gene belongs to the NF-kappa-B inhibitor family, which inhibit NF-kappa-B by complexing with, and trapping it in the cytoplasm. Phosphorylation of serine residues on these proteins by kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B, which translocates to the nucleus to function as a transcription factor. Alternatively spliced transcript variants have been found for this gene.
Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
Isotipo: IgG
Clonalità: Polyclonal
Coniugazione: Unconjugated
Applicazione: IHC
Diluizione: IHC 1:300
Simbolo target: NFKBIB
Ig target: I kappa B beta;I-kappa-B-beta;IkappaBbeta;IKB beta;IkB-B;IkB-beta;IKBB;IKBB;IkBbeta;NF kappa BIB;NF-kappa-B inhibitor beta;NF-kappa-BIB;Nfkbib;Thyroid receptor interacting protein 9;Thyroid receptor-interacting protein 9;TR interacting protein 9;TR-interacting protein 9;TRIP-9;TRIP9
Area di ricerca:Cancer;Epigenetics and Nuclear Signaling;Immunology;Signal Transduction
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