This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family.

Dettagli prodotto

• Codice: E-AB-70223_120μL
• Marca: Elabscience
• Specie target: Human
• Host: Rabbit
• Concentrazione: 190 μg/mL
• Link: Apri link
• Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
• Isotipo: IgG
• Clonalità: Polyclonal
• Coniugazione: Unconjugated
• Applicazione: IHC
• Diluizione: IHC 1:200-1:400
• Simbolo target: SIRT7
• Ig target: NAD dependent deacetylase sirtuin 7;NAD dependent protein deacetylase sirtuin 7;NAD-dependent protein deacetylase sirtuin-7;Regulatory protein SIR2 homolog 7;Silent mating type information regulation 2 homolog;Silent mating type information regulation 2 S.cerevisiae homolog 7;SIR2 L7;SIR2 like protein 7;Sir2 related protein type 7;SIR2;S.CEREVISIAE;HOMOLOG-LIKE 7;SIR2-like protein 7;SIR2L 7;SIR2L7;SIR7;SIRT 7;SIRT7;Sirtuin 7;Sirtuin type 7;Sirtuin7
• Area di ricerca: Cancer;Cardiovascular;Epigenetics and Nuclear Signaling;Metabolism