LDLR (low density lipoprotein receptor) is a member of the LDL receptor gene family and is involved in receptor-mediated endocytosis of specific ligands. The LDLR is a cell surface glycoprotein that scavenges LDL from the blood and regulates plasma LDL cholesterol. The cytoplasmic domain of the LDL receptor is necessary for the receptor to cluster in coated pits,which promotes the rapid endocytosis of bound LDL. The protein is highly glycosylated through N- and O-linkages and thus migrates at 100 to 160 kDa bands on SDS-PAGE.

Codice: E-AB-70239_200μL | Marca: Elabscience | Confezionamento: 200μL

Specie: Human;Mouse;RatIsotipo: IgGConiugazione: Unconjugated

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Codice: E-AB-70239_200μL
Marca: Elabscience
Specie target: Human;Mouse;Rat
Host: Rabbit
Concentrazione: 1 mg/mL
Link: Apri link
Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
Isotipo: IgG
Clonalità: Polyclonal
Coniugazione: Unconjugated
Applicazione: IHC
Diluizione: IHC 1:200-1:1000
Simbolo target: LDLR
Ig target: FH;FHC;LDL R;LDL receptor;LDLCQ2;Ldlr;LDLR;Low Density Lipoprotein Receptor;Low density lipoprotein receptor class A domain containing protein 3;Low density lipoprotein receptor familial hypercholesterolemia;Low-density lipoprotein receptor
Area di ricerca: Cancer;Cardiovascular;Metabolism;Signal Transduction

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