The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in the inhibition of casein kinase and as a cytokine. Altered expression of this protein is associated with the disease cystic fibrosis. Multiple transcript variants encoding different isoforms have been found for this gene.
Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
Isotipo: IgG
Clonalità: Polyclonal
Coniugazione: Unconjugated
Applicazione: IHC
Diluizione: IHC 1:200-1:800
Simbolo target: S100A8
Ig target: 60B8Ag;AI323541;B8Ag;BEE11;CAGA;Calgranulin-A;Calprotectin L1L subunit;Calprotectin;included;CFAG;CGLA;Chemotactic cytokine CP-10;CP-10;Cystic fibrosis antigen;L1Ag;Leukocyte L1 complex light chain;MA387;MIF;Migration inhibitory factor-related protein 8;MRP-8;Myeloid-related protein 8;Neutrophil cytosolic 7 kDa protein;NIF;p8;Pro-inflammatory S100 cytokine;Protein S100-A8;S100 calcium binding protein A8 (calgranulin A);S100 calcium binding protein A8;S100 calcium-binding protein A8;S100A8;S100A8/S100A9 complex;included;S10A8;Urinary stone protein band A
Area di ricerca:Cancer;Neuroscience
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