NAT-10 (N-acetyltransferase 10) is a nuclear protein that belongs to the UPF0202 family. It has a single N-acetyltransferase domain that likely functions as a histone acetyltransferase. NAT10 functions primarily to regulate the activity of telomerase. It is upregulated in response to DNA damage and is likely to take part in genotoxic resistance and DNA repair. NAT-10 has a high binding potential for the promoter region of TERT which stimulates the production of telomerase. These varieties of function imply that human telomerase complexes have multiple functions rather than specific duties.

Dettagli prodotto

• Codice: E-AB-81427_50μL
• Marca: Elabscience
• Specie target: Human;Rat
• Host: Rabbit
• Concentrazione: 300 μg/mL
• Link: Apri link
• Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
• Isotipo: IgG
• Clonalità: Rabbit Monoclonal
• Clone: R05-1C8
• Coniugazione: Unconjugated
• Applicazione: WB;IF
• Diluizione: WB 1:500-1:1000;IF 1:100-1:200
• Simbolo target: NAT10
• Ig target: ALP;DKFZp434C116;FLJ10774;FLJ12179;FLJ23850;hALP;KIAA1709;N acetyltransferase 10;N acetyltransferase 10 GCN5 related;N acetyltransferase like;N acetyltransferase like protein;N-acetyltransferase 10;NAT10;NAT10;NET43
• Area di ricerca: Cancer;Cell Biology;Epigenetics and Nuclear Signaling;Signal Transduction