synaptophysin (Syn), also known as the major synaptic vesicular protein p38, is a protein encoded by SYP gene in human. It interacts with the basic synaptic vesicles, but when inactivated experimentally in animals, they still express and function normally. Syn reacts with neuroendocrine cells in adrenal medulla, carotid artery, skin, pituitary gland, thyroid gland, lung, pancreas and gastrointestinal mucosa. synaptophysin (Syn) Monoclonal can recognize normal neuroendocrine cells and neuroendocrine tumors. SYN is not expressed together with other neural differential markers and can be used as a differential marker to judge tumor.
Terminal deoxynucleotidetransferase (TdT) is a nuclear polymerase with a molecular weight of about 58 kDa, which is normally expressed in normal thymic cortical cells and blast lymphocytes. TdT is widely used as a marker of lymphocytic leukemia and is strongly expressed in acute lymphoblastic lymphoma/leukemia, which is mainly used for the diagnosis of lymphoblastic lymphoma/leukemia.
Thyroglobulin(TG) is a 330 kDa glycoprotein synthesized by thyroid follicles and expressed in normal thyroid follicular epithelium and glia, thyroid follicular adenoma, thyroid follicular carcinoma and papillary carcinoma. Thyroglobulin(TG) Monoclonal has high tissue specificity and is mainly used in the study of various types of primary and metastatic thyroid follicular epithelial carcinoma. It is a specific marker of normal thyroid tissue and benign and malignant thyroid tumors.
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