Inhibin is a glycoprotein hormone, which is composed of α and β It is composed of two subunits, which are produced by ovarian granulosa cells and can inhibit the production and nuclear secretion of pituitary gonadotropin, α- Inhibin determines its specificity. The is used to study the mechanism tumors of reproductive axis.
INI-1, located on chromosome 22q11.2, is a member of the SWI/SWF chromatin remodeling complex and is expressed in all normal tissues. INI-1 encodes a protein of HSWI/SNF chromatin remodeling complex with unknown function, which is prone to mutation and deletion in malignant rhabdoid tumors (MRT). "In most malignant rhabdoid tumors (including atypical teratoma/rhabdoid tumor of the central nervous system in children) and epithelioid sarcomas, INI-1 is inactivated, and the majority of medulloblastomas and primitive neuroectodermal tumors express INI-1."
Insulin is a hormone secreted by islet cells, which can reduce blood glucose concentration. Insulin Monoclonal is mainly used in the functional classification of insulinoma.
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