Myelin Basic Protein(MBP) is the main component of myelin structural protein. It is expressed in neuroma, neurofibroma, neurodifferentiated tumor (ganglioblastoma, gangliocytoma, paraganglioma), but not in gliomas and gliomas. In neurofibroma, CD57 and GFAP are combined to differentiate neuronevus. MBP +, CD57 +, GFAP +, CD57 -, GFAP - and MBP - in neurofibroma.
Microchromosome maintenance protein 2 (MCM2) is related to the occurrence and development of human nasopharyngeal carcinoma. The expression intensity can reflect the activity of cell DNA replication. The pathogenesis of NPC involves the abnormality of MCM2, which can better reflect the proliferation rule of cancer cells, distinguish non cancer cells and cancer cells, and is closely related to the occurrence and clinical progress of NPC.
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