This gene encodes a member of the acyl-CoA thioesterase family which catalyse the conversion of activated fatty acids to the corresponding non-esterified fatty acid and coenzyme A. Expression of a mouse homolog in brown adipose tissue is induced by low temperatures and repressed by warm temperatures. Higher levels of expression of the mouse homolog has been found in obesity-resistant mice compared with obesity-prone mice, suggesting a role of acyl-CoA thioesterase 11 in obesity. Alternative splicing results in transcript variants.
ACOT1 Antibody detects endogenous levels of total ACOT1.
ACOT2 Antibody detects endogenous levels of total ACOT2.
ACOT4 Antibody detects endogenous levels of total ACOT4.
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