SSCFGGRIDRIGAQSGLGCNSFR(Disulfidebridge:C3-C18)
C83H135N29O30S2
SSCFGGRIDRIGAQSGLGCNS(Disulfidebridge:C3-C19)
A synthesized peptide derived from human ATRIP, corresponding to a region within the internal amino acids.
This gene encodes an essential component of the DNA damage checkpoint. The encoded protein binds to single-stranded DNA coated with replication protein A. The protein also interacts with the ataxia telangiectasia and Rad3 related protein kinase, resulting in its accumulation at intranuclear foci induced by DNA damage. Multiple transcript variants encoding different isoforms have been found for this gene.
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