A synthesized peptide derived from human RAD51L1, corresponding to a region within the internal amino acids.
A synthesized peptide derived from human RAD51L3, corresponding to a region within C-terminal amino acids.
A synthetic peptide from human RAD51
A synthesized peptide derived from human RAD52, corresponding to a region within the internal amino acids.
The protein encoded by this gene shares similarity with Saccharomyces cerevisiae Rad52, a protein important for DNA double-strand break repair and homologous recombination. This gene product was shown to bind single-stranded DNA ends, and mediate the DNA-DNA interaction necessary for the annealing of complementary DNA strands. It was also found to interact with DNA recombination protein RAD51, which suggested its role in RAD51 related DNA recombination and repair.
A synthesized peptide derived from human RAD54, corresponding to a region within C-terminal amino acids.
A synthesized peptide derived from human RAD54B, corresponding to a region within the internal amino acids.
The protein encoded by this gene belongs to the DEAD-like helicase superfamily. It shares similarity with Saccharomyces cerevisiae RAD54 and RDH54, both of which are involved in homologous recombination and repair of DNA. This protein binds to double-stranded DNA, and displays ATPase activity in the presence of DNA. This gene is highly expressed in testis and spleen, which suggests active roles in meiotic and mitotic recombination. Homozygous mutations of this gene were observed in primary lymphoma and colon cancer.
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